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. 1969 Oct;64(2):573-7.
doi: 10.1073/pnas.64.2.573.

A mechanism for genetic recombination generating one parent and one recombinant

T Boon, N D Zinder

A mechanism for genetic recombination generating one parent and one recombinant

T Boon et al. Proc Natl Acad Sci U S A. 1969 Oct.

Abstract

A mechanism is proposed for generating one parental and one recombinant genome in a single recombination event between two DNA molecules. Three stages of the event are described: initiation, replication, and return. Initiation requires breakage and joining of strands. Replication proceeds through a biparental "replication fork" generated in initiation. Return also involves breakage and joining of strands. Some of the implications of such a mechanism for genetic recombination are discussed.

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