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. 1969 Oct;64(2):600-4.
doi: 10.1073/pnas.64.2.600.

Molecular hybridization of radioactive DNA to the DNA of cytological preparations

M L Pardue, J G Gall

Molecular hybridization of radioactive DNA to the DNA of cytological preparations

M L Pardue et al. Proc Natl Acad Sci U S A. 1969 Oct.

Abstract

A method is presented for detecting the cellular location of specific DNA fractions. The technique involves the hybridization of a radioactive test DNA in solution to the stationary DNA of a cytological preparation. Sites of DNA binding are then detected by autoradiography. Experiments with DNA of the toad Xenopus are described.

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References

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