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Comparative Study
. 1979 Jul;66(3):361-3.
doi: 10.1111/j.1476-5381.1979.tb10838.x.

Different effects of current strength on inhibitory responses of the mouse vas deferens to methionine- and leucine-enkephalin

S L Hart, I Kitchen, P R Waddell
Comparative Study

Different effects of current strength on inhibitory responses of the mouse vas deferens to methionine- and leucine-enkephalin

S L Hart et al. Br J Pharmacol. 1979 Jul.

Abstract

The inhibitory potency of methionine (Met)-enkephalin on the field-stimulated mouse vas deferens was greatly increased by a reduction in current strength whilst that of leucine (Leu)-enkephalin increased only slightly. All currents were submaximal and all muscle twitches were neuronally evoked. These results suggest that inhibitory effects of Met- and Leu-enkephalin in the mouse vas deferens are not commonly mediated and provide a rapid method for ascertaining heterogeneity of enkephalin extracts.

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References

    1. J Physiol. 1978 Oct;283:23-39 - PubMed
    1. Eur J Pharmacol. 1977 May 15;43(2):107-16 - PubMed
    1. Nature. 1977 Jun 9;267(5611):495-9 - PubMed
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    1. FEBS Lett. 1977 Mar 1;74(2):182-4 - PubMed

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