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. 1970 Mar;65(3):721-8.
doi: 10.1073/pnas.65.3.721.

On the interactions of lipids and proteins in the red blood cell membrane

M Glaser, H Simpkins, S J Singer, M Sheetz, S I Chan

On the interactions of lipids and proteins in the red blood cell membrane

M Glaser et al. Proc Natl Acad Sci U S A. 1970 Mar.

Abstract

The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the proteins of the membranes can change structure independently of one another, suggesting a mosaic pattern for the organization of the lipids and proteins in membranes.

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