doi: 10.1016/0022-1759(75)90120-9.
Peritoneal macrophages as target cells for measuring virus-specific T cell mediated cytotoxicity in vitro
- PMID: 52680
- DOI: 10.1016/0022-1759(75)90120-9
Item in Clipboard
Peritoneal macrophages as target cells for measuring virus-specific T cell mediated cytotoxicity in vitro
J Immunol Methods.
1975 Sep.
Abstract
In inbred or outbred mice lysis of virally modified cells by thymus-derived lymphocytes occurs only within a H-2 compatible system. Peritoneal macrophages provide a convenient source of syngeneic target cells. They are readily infected in vitro with LCM virus, and show high levels of specific 51Cr release when exposed to T cells from LCM immune mice.
Similar articles
-
H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T-cell specificities are associated with structures coded for in H-2K or H-2D;J Exp Med. 1975 Jun 1;141(6):1427-36. doi: 10.1084/jem.141.6.1427. J Exp Med. 1975. PMID: 47901 Free PMC article.
-
Capacity of sensitized thymus-derived lymphocytes to induce fatal lymphocytic choriomeningitis is restricted by the H-2 gene complex.J Immunol. 1975 Jan;114(1 Pt 1):30-3. J Immunol. 1975. PMID: 1078677
-
Functional heterogeneity of lymphocytic choriomeningitis virus-specfic T lymphocytes. I. Identification of effector amd memory subsets.J Exp Med. 1975 Apr 1;141(4):866-81. J Exp Med. 1975. PMID: 47887 Free PMC article.
-
Major transplantation antigens, viruses, and specificity of surveillance T cells.Contemp Top Immunobiol. 1977;7:179-220. doi: 10.1007/978-1-4684-3054-7_5. Contemp Top Immunobiol. 1977. PMID: 69515 Review. No abstract available.
-
Function of macrophages as antigen presenting cells.Springer Semin Immunopathol. 1980 Aug;3(2):247-64. doi: 10.1007/BF02053977. Springer Semin Immunopathol. 1980. PMID: 6168025 Review. No abstract available.
Cited by
-
H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice.J Exp Med. 1976 Feb 1;143(2):437-43. doi: 10.1084/jem.143.2.437. J Exp Med. 1976. PMID: 1082490 Free PMC article.
-
Protective activity of secondary effector T cells generated in vitro against ectromelia virus infection in vivo.Clin Exp Immunol. 1977 Dec;30(3):338-46. Clin Exp Immunol. 1977. PMID: 203425 Free PMC article.
-
Consequences of a single Ir-gene defect for the pathogenesis of lymphocytic choriomeningitis.Immunogenetics. 1985;21(6):581-9. doi: 10.1007/BF00395882. Immunogenetics. 1985. PMID: 3874159
-
Cytotoxic cells induced after Chlamydia psittaci infection in mice.Infect Immun. 1982 Mar;35(3):1011-7. doi: 10.1128/iai.35.3.1011-1017.1982. Infect Immun. 1982. PMID: 7068208 Free PMC article.
-
Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.J Exp Med. 1990 Apr 1;171(4):1315-32. doi: 10.1084/jem.171.4.1315. J Exp Med. 1990. PMID: 2139102 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
