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. 1970 Jul;66(3):807-14.
doi: 10.1073/pnas.66.3.807.

Precipitation of proteins by vinblastine and calcium ions

L Wilson, J Bryan, A Ruby, D Mazia

Precipitation of proteins by vinblastine and calcium ions

L Wilson et al. Proc Natl Acad Sci U S A. 1970 Jul.

Abstract

We have found that vinblastine sulfate can precipitate a number of proteins in addition to microtubule protein. Those proteins which precipitate with vinblastine sulfate, all of which were derived from structure, also precipitate with Ca(2+) ions. Our results suggest that vinblastine sulfate, presumably acting as a cation, precipitates proteins by combining with sites which can also combine with Ca(2+) ions.

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References

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