Protein chain initiation in rabbit reticulocytes
- PMID: 5273453
- PMCID: PMC335817
- DOI: 10.1073/pnas.66.4.1282
Protein chain initiation in rabbit reticulocytes
Abstract
About 15% of the nascent alpha-chains isolated from in vivo labeled rabbit reticulocytes have methionine as their amino terminal amino acid. The methionine is predominantly on the shortest nascent chains, suggesting that methionine initiates the synthesis of rabbit hemoglobin and is rapidly removed during further synthesis.
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