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. 1970 Aug;66(4):1282-9.
doi: 10.1073/pnas.66.4.1282.

Protein chain initiation in rabbit reticulocytes

Protein chain initiation in rabbit reticulocytes

D B Wilson et al. Proc Natl Acad Sci U S A. 1970 Aug.

Abstract

About 15% of the nascent alpha-chains isolated from in vivo labeled rabbit reticulocytes have methionine as their amino terminal amino acid. The methionine is predominantly on the shortest nascent chains, suggesting that methionine initiates the synthesis of rabbit hemoglobin and is rapidly removed during further synthesis.

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