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. 1979 May-Jul;4(3-4):245-8.
doi: 10.1016/0376-8716(79)90005-x.

Regional differences in high-affinity choline uptake in brain after acute and chronic treatment with ethanol

W A Hunt, E Majchrowicz

Regional differences in high-affinity choline uptake in brain after acute and chronic treatment with ethanol

W A Hunt et al. Drug Alcohol Depend. 1979 May-Jul.

Abstract

A single dose of ethanol has been shown to affect both striatal and hippocampal high-affinity choline uptake. This effect is probably mediated through effects of ethanol on acetylcholine release. Choline uptake has also been shown to be altered in ethanol-dependent animals, and these effects may be coupled to alterations in dopamine neurons which are produced by chronic ethanol feeding and withdrawal.

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