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. 1971 Jan;68(1):234-9.
doi: 10.1073/pnas.68.1.234.

Genes for neuronal properties expressed in neuroblastoma x L cell hybrids

J Minna, P Nelson, J Peacock, D Glazer, M Nirenberg

Genes for neuronal properties expressed in neuroblastoma x L cell hybrids

J Minna et al. Proc Natl Acad Sci U S A. 1971 Jan.

Abstract

Neuroblastoma cells with electrically excitable membranes were fused with electrically passive L cells having a hitherto undescribed electrical marker. Hybrid cells, examined 10-40 generations after fusion, were found to be electrically excitable. The results show that at least a part of the genetic information for neuron differentiation can be functionally expressed in N x L hybrid cells. Evidence for the regulation of action potential components was also found.

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References

    1. Proc Natl Acad Sci U S A. 1967 Mar;57(3):615-21 - PubMed
    1. Biochem Genet. 1969 Apr;3(2):151-62 - PubMed
    1. Exp Cell Res. 1966 Jan;41(1):190-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 Sep;58(3):1104-11 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Sep;67(1):247-54 - PubMed

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