Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Mar;68(3):645-52.
doi: 10.1073/pnas.68.3.645.

Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts

D Paul, A Lipton, I Klinger

Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts

D Paul et al. Proc Natl Acad Sci U S A. 1971 Mar.

Abstract

Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and transformed 3T3 cells in serum-free medium, probably without inducing growth of the cells. These factors are separated and partially purified.

PubMed Disclaimer

References

    1. J Cell Physiol. 1965 Dec;66(3):325-33 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 May;60(1):126-33 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 May;60(1):300-4 - PubMed
    1. Proc Natl Acad Sci U S A. 1969 Apr;62(4):1074-6 - PubMed
    1. Nature. 1970 Aug 22;227(5260):798-801 - PubMed

LinkOut - more resources