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. 1971 Feb;68(2):342-6.
doi: 10.1073/pnas.68.2.342.

DNA-induced transformation in Drosophila: genetic analysis of transformed stocks

A S Fox, S B Yoon, W M Gelbart

DNA-induced transformation in Drosophila: genetic analysis of transformed stocks

A S Fox et al. Proc Natl Acad Sci U S A. 1971 Feb.

Abstract

The exosome model of transformation in Drosophila melanogaster proposes that DNA fragments enter the cells of treated individuals and become firmly associated with their homologous chromosome segments, but are never integrated into the linear structure of the chromosome. This paper reports results that validate two central predictions of the model: (a) the introduced genetic information usually maps precisely at the site of the target locus, and (b) the original chromosomal information is still present at that site.

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References

    1. Genetics. 1965 Sep;52(3):503-12 - PubMed
    1. Genetics. 1966 May;53(5):897-911 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Nov;67(3):1608-15 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Dec;67(4):1834-8 - PubMed
    1. Genet Res. 1965 Jul;6:157-62 - PubMed

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