doi: 10.1038/258121a0.
Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange
- PMID: 52847
- DOI: 10.1038/258121a0
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Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange
Nature.
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Abstract
A staining technique that detects sister chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens-carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens.
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