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. 1971 Jun;68(6):1321-5.
doi: 10.1073/pnas.68.6.1321.

An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA

J E Darnell, R Wall, R J Tushinski

An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA

J E Darnell et al. Proc Natl Acad Sci U S A. 1971 Jun.

Abstract

Messenger RNA from HeLa cells contains, as part of the polynucleotide chain, RNase-resistant sequences that are labeled by adenosine but not by uridine. Heterogeneous nuclear RNA also contains adenylate-rich RNase-resistant regions, but in lower proportion than messenger RNA. Hybridization to DNA of (32)P-labeled messenger RNA reveals that some of the adenylate-rich region is included in the rapidly-hybridizing fraction.

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References

    1. J Mol Biol. 1968 Jul 14;35(1):37-59 - PubMed
    1. Science. 1969 Jul 25;165(3891):349-57 - PubMed
    1. J Mol Biol. 1970 Dec 28;54(3):517-35 - PubMed
    1. J Biol Chem. 1969 Mar 10;244(5):1314-24 - PubMed
    1. J Mol Biol. 1967 Jun 14;26(2):211-25 - PubMed

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