Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1971 Dec;68(12):3219-22.
doi: 10.1073/pnas.68.12.3219.

Synaptogenesis in reaggregating brain cell culture

N W Seeds, A E Vatter

Synaptogenesis in reaggregating brain cell culture

N W Seeds et al. Proc Natl Acad Sci U S A. 1971 Dec.

Abstract

Dissociated cells from embryonic mouse brain reassociate in rotation culture to form highly organized aggregates. Electron microscopic observations of aggregates show the presence of synapses that mature and increase in number during culture. Apparent myelination of axons is observed in the aggregates after 5 weeks of culture. Thus, brain cell aggregates perform two highly specialized morphological events that are characteristic of mouse brain differentiation.

PubMed Disclaimer

References

    1. J Ultrastruct Res. 1967 Jan;17(1):158-75 - PubMed
    1. Experientia. 1967 Mar 15;23(3):199-200 - PubMed
    1. Brain Res. 1967 Dec;6(4):716-27 - PubMed
    1. Brain Res. 1967 Dec;6(4):728-49 - PubMed
    1. J Cell Biol. 1968 Sep;38(3):615-27 - PubMed

LinkOut - more resources