A novel closed-circular mitochondrial DNA with properties of a replicating intermediate
- PMID: 5289384
- PMCID: PMC389395
- DOI: 10.1073/pnas.68.9.2252
A novel closed-circular mitochondrial DNA with properties of a replicating intermediate
Abstract
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.
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