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. 1971 Sep;68(9):2252-7.
doi: 10.1073/pnas.68.9.2252.

A novel closed-circular mitochondrial DNA with properties of a replicating intermediate

A novel closed-circular mitochondrial DNA with properties of a replicating intermediate

H Kasamatsu et al. Proc Natl Acad Sci U S A. 1971 Sep.

Abstract

A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.

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