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. 1968 Jun;3(5):413-21.

Factors influencing the immune response. 3. The blocking effect of Corynebacterium parvum upon the induction of acquired immunological unresponsiveness to bovine serum albumin in the adult rabbit

R N Pinckard, D M Weir, W H McBride

Factors influencing the immune response. 3. The blocking effect of Corynebacterium parvum upon the induction of acquired immunological unresponsiveness to bovine serum albumin in the adult rabbit

R N Pinckard et al. Clin Exp Immunol. 1968 Jun.

Abstract

The intravenous injection of 10 mg aggregate-free, centrifuged bovine albumin into adult rabbits has been shown to induce an unresponsive state to bovine serum albumin (BSA) in the majority of rabbits. An intravenous injection of 15 mg of a heat-killed suspension of Corynebacterium parvum either 6 days prior to or simultaneously with centrifuged bovine albumin has been shown to significantly block the induction of unresponsiveness to BSA. Some effects of C. parvum upon the lymphoreticular tissues in the rabbit are reported.

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References

    1. J Immunol. 1967 Sep;99(3):624-8 - PubMed
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    1. J Immunol. 1965 Oct;95(4):718-21 - PubMed
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