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. 1970 Oct 10;4(5727):69-72.
doi: 10.1136/bmj.4.5727.69.

Osteomalacia with long-term anticonvulsant therapy in epilepsy

Osteomalacia with long-term anticonvulsant therapy in epilepsy

C E Dent et al. Br Med J. .

Abstract

The investigation and treatment of osteomalacia are described in four patients with epilepsy treated with long-term anticonvulsant therapy. It is suggested that drug-mediated enzyme induction may be the mechanism responsible by causing a greatly increased inactivation of vitamin D in these patients.

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