Osteomalacia with long-term anticonvulsant therapy in epilepsy
- PMID: 5312062
- PMCID: PMC1819593
- DOI: 10.1136/bmj.4.5727.69
Osteomalacia with long-term anticonvulsant therapy in epilepsy
Abstract
The investigation and treatment of osteomalacia are described in four patients with epilepsy treated with long-term anticonvulsant therapy. It is suggested that drug-mediated enzyme induction may be the mechanism responsible by causing a greatly increased inactivation of vitamin D in these patients.
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