Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1970 Oct 10;4(5727):69-72.
doi: 10.1136/bmj.4.5727.69.

Osteomalacia with long-term anticonvulsant therapy in epilepsy

C E Dent, A Richens, D J Rowe, T C Stamp

Osteomalacia with long-term anticonvulsant therapy in epilepsy

C E Dent et al. Br Med J. .

Abstract

The investigation and treatment of osteomalacia are described in four patients with epilepsy treated with long-term anticonvulsant therapy. It is suggested that drug-mediated enzyme induction may be the mechanism responsible by causing a greatly increased inactivation of vitamin D in these patients.

PubMed Disclaimer

References

    1. J Clin Pathol. 1965 Sep;18(5):593-8 - PubMed
    1. Vitam Horm. 1967;25:315-67 - PubMed
    1. Am J Clin Nutr. 1969 Apr;22(4):437-46 - PubMed
    1. J Clin Invest. 1969 Jul;48(7):1273-9 - PubMed
    1. Arch Intern Med. 1969 Oct;124(4):442-50 - PubMed

LinkOut - more resources