doi: 10.2337/diab.24.12.1081.
Fast and slow axoplasmic flow in sciatic nerve of diabetic rats
- PMID: 53167
- DOI: 10.2337/diab.24.12.1081
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Fast and slow axoplasmic flow in sciatic nerve of diabetic rats
Diabetes.
1975 Dec.
Abstract
Accumulation of acetylcholinesterase (AChE) and choline acetylase (ChAc) activities proximal to a tie placed on the sciatic nerve was measured in control, untreated diabetic, and insulin-treated diabetic rats. In the diabetic animals AChE accumulation was reduced by about 20% and ChAc accumulation by about 40%. Insulin treatment eliminated the impairment. It remains an open question whether these reversible functional changes in rat have any counterpart in the diabetic neuropathy of man.
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