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. 1971 May;7(6):175-8.

Hypogonadotropic hypogonadism in patients with multiple congenital defects

  • PMID: 5317488

Hypogonadotropic hypogonadism in patients with multiple congenital defects

C W Bardin. Birth Defects Orig Artic Ser. 1971 May.

Abstract

Several syndromes have been reviewed in which hypogonadotropism is associated with multiple somatic and neurologic anomalies. A review of the literature indicates that these conditions demonstrate considerable clinical heterogeneity. In the several hypogonadotropic syndromes described to date autosomal and X-linked transmission have been implicated in the inheritance of the hypogonadism. The associated neurologic and somatic anomalies may segregate independent of the hypogonadism and in some instances may have a separate mode of transmission.

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