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Clinical Trial
. 1975 Nov 1;2(7940):842-4.
doi: 10.1016/s0140-6736(75)90235-4.

Controlled trial of bromocriptine, quinoestrol, and placebo in suppression of puerperal lactation

S Walker, G Groom, R H Davis, B M Hibbard, K Griffiths
Clinical Trial

Controlled trial of bromocriptine, quinoestrol, and placebo in suppression of puerperal lactation

S Walker et al. Lancet. .

Abstract

2-bromo-alpha-ergocryptine (bromocriptine) in a dosage of 2-5 mg twice daily caused a rapid fall in plasma prolactin. It was more effective than either a single dose of 4 mg quinoestrol or a placebo in suppressing puerperal lactation, as judged by milk flow and the relief of breast pain and congestion. Patients who received quinoestrol were more comfortable than those who received placebo.

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