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. 1979 Dec;140(3):1123-5.
doi: 10.1128/jb.140.3.1123-1125.1979.

Local anesthetics block induction of the Pseudomonas alk regulon

S A Benson

Local anesthetics block induction of the Pseudomonas alk regulon

S A Benson. J Bacteriol. 1979 Dec.

Abstract

The local anesthetics procaine and piperocaine blocked induction of the plasmid-determined enzymatic activities involved in the metabolism of n-alkanes in Pseudomonas putida. Procaine reversibly inhibited existing alkane hydroxylase activity. Induction of a soluble aliphatic amidase activity was not affected. These results support the hypothesis that induction of the plasmid-determined alkane metabolic system in P. putida involves a membrane component(s).

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References

    1. Anesthesiology. 1977 May;46(5):327-32 - PubMed
    1. J Bacteriol. 1977 Nov;132(2):622-7 - PubMed
    1. J Bacteriol. 1977 Nov;132(2):614-21 - PubMed
    1. J Bacteriol. 1977 Aug;131(2):431-7 - PubMed
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