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. 1966 Jul;100(1):1-6.
doi: 10.1042/bj1000001.

The role of shikimic acid in the biosynthesis of vitamin K2

G B Cox, F Gibson

The role of shikimic acid in the biosynthesis of vitamin K2

G B Cox et al. Biochem J. 1966 Jul.

Abstract

1. Shikimic acid was shown to be a precursor of vitamin K(2) (MK-8) in Escherichia coli. 2. The benzene ring of the naphthaquinone arises from shikimic acid. 3. The methyl group of methionine is incorporated into vitamin K(2). 4. A scheme relating the biosynthesis of vitamin K(2) and ubiquinone to the general pathway of aromatic biosynthesis is proposed.

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