Genetic recombination in Escherichia coli: clone heterogeneity and the kinetics of segregation
- PMID: 5339155
- DOI: 10.1126/science.157.3786.319
Genetic recombination in Escherichia coli: clone heterogeneity and the kinetics of segregation
Abstract
Several recombinant types may be produced from a single Escherichia coli zygote when the donor parent is Hfr-Hayes and segregation is delayed; usually only one type is produced with Hfr-Cavalli. Statistical experiments confirm well-known pedigree analyses by micromanipulation and suggest that DNA synthesis is required before final genetic integration.
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