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. 1967 Mar;15(2):257-65.
doi: 10.1128/am.15.2.257-265.1967.

Kinetics and mechanism of bacterial disinfection by chlorine dioxide

M A Benarde, W B Snow, V P Olivieri, B Davidson

Kinetics and mechanism of bacterial disinfection by chlorine dioxide

M A Benarde et al. Appl Microbiol. 1967 Mar.

Abstract

Survival data are presented for a fecal strain of Escherichia coli exposed to three concentrations of chlorine dioxide at four temperatures. Chick's first-order reaction equation is generalized to a pseudo nth-order model. Nonlinear least squares curve-fitting of the survival data to the nth order model was performed on an analogue computer. The data were observed to follow fractional order kinetics with respect to survival concentration, with an apparent activation energy of 12,000 cal/mole. Initial experiments support the thesis that the mechanism of chlorine dioxide kill occurs via disruption of protein synthesis.

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References

    1. Appl Microbiol. 1965 Sep;13(5):776-80 - PubMed
    1. Z Hyg Infektionskr. 1953;138(2):155-66 - PubMed
    1. J Bacteriol. 1948 Apr;55(4):451-8 - PubMed

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