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Comparative Study
. 1979 Oct 1;183(1):189-92.
doi: 10.1042/bj1830189.

Comparison of radioactive peptides obtained from specifically labelled human renal and placental alkaline phosphatases

K B Whitaker, D W Moss
Comparative Study

Comparison of radioactive peptides obtained from specifically labelled human renal and placental alkaline phosphatases

K B Whitaker et al. Biochem J. .

Abstract

Peptides with different chromatographic and electrophoretic properties were obtained from human placental and renal alkaline phosphatases by tryptic digestion of the enzymes labelled with radioactive orthophosphate at their active centres. These results provide structural evidence for the distinct genetic origins of the two isoenzymes that had previously been inferred from their different properties and from the observed phenotypic variation of placental phosphatase.

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