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. 1969 Nov;37(3):733-7.
doi: 10.1111/j.1476-5381.1969.tb08512.x.

Carbon tetrachloride metabolism in the rabbit

Carbon tetrachloride metabolism in the rabbit

J S Fowler. Br J Pharmacol. 1969 Nov.

Abstract

1. Carbon tetrachloride was administered by stomach tube to rabbits and its distribution in fat, liver, kidney and muscle studied by gas liquid chromatography, during the next 48 hr.2. Chloroform, hexachloroethane and two unidentified chlorinated metabolites were detected in the tissues.3. Hexachloroethane may arise by dimerization of free trichloromethyl radicals.

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References

    1. J Clin Invest. 1969 Jan;48(1):203-9 - PubMed
    1. Biochem Pharmacol. 1969 Mar;18(3):645-50 - PubMed
    1. Br J Pharmacol. 1969 Mar;35(3):530-42 - PubMed
    1. J Pharmacol Exp Ther. 1961 Dec;134:311-9 - PubMed

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