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. 1979;53(1):107-9.
doi: 10.1007/BF00289459.

Demonstration of Y/autosomal translocations using distamycin A

Demonstration of Y/autosomal translocations using distamycin A

M Schmid. Hum Genet. 1979.

Abstract

The condensation of the brightly fluorescing Y-heterochromatin is prevented by cultivating leukocytes in a medium containing distamycin A. This technique provides a reliable method for the identification of those Y/autosomal translocations in which Y heterochromatin is involved. A case of a familiar Y/22 translocation and the distamycin A technique are described.

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