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. 1969 Nov;4(5):763-8.
doi: 10.1128/JVI.4.5.763-768.1969.

Biophysical properties of Australia antigen

J L Gerin, R H Purcell, M D Hoggan, P V Holland, R M Chanock

Biophysical properties of Australia antigen

J L Gerin et al. J Virol. 1969 Nov.

Abstract

Biophysical studies with Australia complement-fixing (CF) antigen showed it to be a particle with a buoyant density of 1.20 g/cm(3) in CsCl, a sedimentation coefficient of 110, and an average diameter of 25 nm. The CF antigen was not inactivated by ether, 1% deoxycholate, 1% Tween 80 or overnight heating at 56 C. The antigen was unstable when treated with 1% sodium dodecyl sulfate. A procedure is described for the isolation and partial purification of Australia antigen from serum by using isopycnic banding and rate separation techniques. Treatment of the 1.20 g/cm(3) Australia antigen with 1% Tween 80 yielded a minor peak of CF activity with a buoyant density of 1.39 g/cm(3) in CsCl.

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References

    1. Blood. 1966 Mar;27(3):297-309 - PubMed
    1. Ann Intern Med. 1967 May;66(5):924-31 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Jul;60(3):814-21 - PubMed
    1. Bull N Y Acad Med. 1968 Dec;44(12):1566-86 - PubMed
    1. J Gen Virol. 1969 Jan;4(1):37-46 - PubMed

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