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Comparative Study
. 1975 Dec 13;2(7946):1176-8.
doi: 10.1016/s0140-6736(75)92660-4.

R factors in gentamicin-resistant organisms causing hospital infection

A S Richmond, M S Simberkoff, J J Rahal Jr, S Schaefler
Comparative Study

R factors in gentamicin-resistant organisms causing hospital infection

A S Richmond et al. Lancet. .

Abstract

An abrupt increase in gentamicin-resistant isolates was noted in the Manhattan Veterans Administration Hospital in 1973 and 1974. Bacteraemic infection occurred in 17 patients, 9 of whom died. R factors mediating gentamicin resistance were demonstrated in 34 of 36 strains. Organisms from 9 of 11 patients transferred a resistance pattern common to all other isolates from that patient, suggesting in-vivo interbacterial spread of the R factor.

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