Gastrointestinal cancer and nutrition
- PMID: 5366239
- PMCID: PMC1553006
- DOI: 10.1136/gut.10.12.1031
Gastrointestinal cancer and nutrition
Abstract
The hypothesis upon which this study was based is that there is a relationship between mortality from gastrointestinal cancer and living standards. On this basis we found significant correlations between the intake of animal proteins and the mortality rates for gastric and intestinal cancer. The negative correlation coefficient (r = - 0.85) is an expression of the inverse relationship between gastric and intestinal cancer mortality rates. This inverse relationship is also expressed as the correlation between the food intake, expressed by the intake of animal protein, and the respective mortality rates. The higher the food intake, the lower the gastric cancer mortality rate but the higher the intestinal cancer mortality rate. We do not claim that this relationship discovered by correlation analysis is a causal one. On the basis of this study it cannot therefore be said that food intake has a direct effect on the development of gastrointestinal cancer. In this respect our findings can only be a signal for further studies. Secondly no time lag has been proved between food intake and the mortality rate for intestinal cancer. The findings relating to gastric cancer do not contradict the hypothesis of a time lag.
Similar articles
-
[Effect of bile on the development of tumors of the stomach and small intestine induced in rats by N-methyl-N-nitro-N-nitrosoguanidine].Vopr Onkol. 1987;33(1):83-9. Vopr Onkol. 1987. PMID: 3811314 Russian.
-
The role of dietary factors in the intestinal and diffuse histologic subtypes of gastric adenocarcinoma: a case-control study in the U.S.Cancer. 1997 Sep 15;80(6):1021-8. Cancer. 1997. PMID: 9305701
-
[Role of nutrition and alcoholism in the genesis of cancer of the gastrointestinal tract].Vopr Onkol. 1988;34(7):861-4. Vopr Onkol. 1988. PMID: 3420834 Russian. No abstract available.
-
Nutrition and gastric cancer risk: an update.Nutr Rev. 2008 May;66(5):237-49. doi: 10.1111/j.1753-4887.2008.00029.x. Nutr Rev. 2008. PMID: 18454810 Review.
-
Dietary factors in the aetiology of gastrointestinal cancer.J Hum Nutr. 1978 Dec;32(6):455-65. J Hum Nutr. 1978. PMID: 366021 Review.
Cited by
-
Colonic cancer--hypotheses of causation, dietary prophylaxis, and future research.Am J Dig Dis. 1976 Oct;21(10):910-7. doi: 10.1007/BF01072087. Am J Dig Dis. 1976. PMID: 1015500
-
Influence of diets high and low in animal fat on bowel habit, gastrointestinal transit time, fecal microflora, bile acid, and fat excretion.J Clin Invest. 1978 Apr;61(4):953-63. doi: 10.1172/JCI109020. J Clin Invest. 1978. PMID: 659584 Free PMC article.
-
Comparison of the fecal microflora of Seventh-Day Adventists with individuals consuming a general diet. Implications concerning colonic carcinoma.Ann Surg. 1977 Jul;186(1):97-100. doi: 10.1097/00000658-197707000-00013. Ann Surg. 1977. PMID: 327955 Free PMC article. Clinical Trial.
-
Faecal bile acids and clostridia in the aetiology of colorectal cancer.Br J Cancer. 1980 Jun;41(6):923-8. doi: 10.1038/bjc.1980.170. Br J Cancer. 1980. PMID: 7426316 Free PMC article.
-
Dietary factors in aetiology and prevention of cancer in man.Environ Geochem Health. 1990 Sep;12(3):221-38. doi: 10.1007/BF01782985. Environ Geochem Health. 1990. PMID: 24202632
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources