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. 1969 Sep;18(3):406-9.
doi: 10.1128/am.18.3.406-409.1969.

Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp

Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp

Y Ueno et al. Appl Microbiol. 1969 Sep.

Abstract

Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of (14)C-labeled luteoskyrin was 2-(14)C-malonate.

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