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Comparative Study
. 1979 Dec;17(11-12):1151-8.
doi: 10.1007/BF00504352.

Amino acid sequence differences in pancreatic ribonucleases from water buffalo breeds from Indonesia and Italy

A Sidik, B Martena, J J Beintema
Comparative Study

Amino acid sequence differences in pancreatic ribonucleases from water buffalo breeds from Indonesia and Italy

A Sidik et al. Biochem Genet. 1979 Dec.

Abstract

The amino acid sequences of the pancreatic ribonucleases from river-breed water buffaloes from Italy and swamp-breed water buffaloes from Indonesia differ at three positions. One of the differences involves a replacement of asparagine-34, with covalently attached carbohydrate on all molecules, in the river-breed enzyme by serine in the swamp-breed enzyme. The ribonuclease content of the pancreas differs considerably between breeds and is lower in river buffaloes. A ribonuclease preparation from two swamp buffaloes contained a minor glycosylated component. Preliminary evidence was obtained that the amino acid sequence of this component has factors in common with the main component of the swamp-breed ribonuclease and with the river-breed enzyme.

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References

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