Allotype exclusion in uniform rabbit antibody to streptococcal carbohydrate
- PMID: 5419853
- PMCID: PMC2138788
- DOI: 10.1084/jem.131.2.343
Allotype exclusion in uniform rabbit antibody to streptococcal carbohydrate
Abstract
Rabbit antibodies to streptococcal polysaccharide are described which show selectivity of expression of the allotypic specificities on both the heavy (H) and light (L) chains. One of these antibodies binds weakly to Sephadex. A purification method based on this binding has yielded antibody completely lacking any group a allotypic marker on its H chains.
