Homozygous Hb J Tongariki: evidence for only one alpha chain structural locus in Melanesians
- PMID: 5427353
- DOI: 10.1126/science.169.3941.194
Homozygous Hb J Tongariki: evidence for only one alpha chain structural locus in Melanesians
Abstract
A high frequency of Hb J Tongariki (alpha 115 Ala --> Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hbalpha structural locus is present.
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