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. 1975:30:310-5.

The use of hepatitis B immunoglobulin in the Netherlands

H W Reesink, W J Duimel, J E de Boer, E H van Elven, H G Brummelhuis
  • PMID: 54274

The use of hepatitis B immunoglobulin in the Netherlands

H W Reesink et al. Dev Biol Stand. 1975.

Abstract

Hepatitis B immunoglobulin (HBIg) was administered to 241 patients contaminated with HBAg positive material; 116 persons were followed up for 7 months after the HBIg injection. Only 4 (3.4%) cases of hepatitis B with jaundice and demonstrable HBAg occurred and 15 (12.9%) cases of subclinical hepatitis B were observed. HBIg is well tolerated. Passively transferred HBAb were demonstrable for 2-3 months and no chronic carriers of HBAg were seen after administration of HBIg.

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