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. 1970 Aug;103(2):364-9.
doi: 10.1128/jb.103.2.364-369.1970.

Induction of kynureninase in Neurospora

J R Turner, W A Sorsoli, W H Matchett

Induction of kynureninase in Neurospora

J R Turner et al. J Bacteriol. 1970 Aug.

Abstract

Induction of kynureninase in a homogeneous population of mycelia in balanced growth was studied. Induced synthesis of enzyme was apparent 10 min after addition of inducers (tryptophan, kynurenine, and N-formylkynurenine). Experiments with cycloheximide-inhibited cells indicated that initiation of message transcription occurred about 4 min after addition of inducers. Lifetime of the message in the absence of inducer was of the order of 5 min. Experiments with mutants showed that N-formylkynurenine was the probable inducer of physiological importance.

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References

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