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Clinical Trial
. 1975 Dec;12(6):1290-4.
doi: 10.1128/iai.12.6.1290-1294.1975.

Vi antigen from Salmonella typhosa and immunity against typhoid fever. 11. Safety and antigenicity in humans

D M Levin, K H Wong, H Y Reynolds, A Sutton, R S Northrup
Clinical Trial

Vi antigen from Salmonella typhosa and immunity against typhoid fever. 11. Safety and antigenicity in humans

D M Levin et al. Infect Immun. 1975 Dec.

Abstract

Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 mug were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 X 10(8) bacteria per dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody responses.

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References

    1. Proc Soc Exp Biol Med. 1953 Apr;82(4):593-8 - PubMed
    1. Am J Hyg. 1953 Sep;58(2):148-64 - PubMed
    1. Am J Hyg. 1954 Jul;60(1):52-62 - PubMed
    1. Tex Rep Biol Med. 1963;21:214-29 - PubMed
    1. J Immunol. 1964 Feb;92:281-5 - PubMed

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