Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1970 Mar;101(3):881-4.
doi: 10.1128/jb.101.3.881-884.1970.

Conversion of histidine to hercynine by Neurospora crassa

V N Reinhold, Y Ishikawa, D B Melville

Conversion of histidine to hercynine by Neurospora crassa

V N Reinhold et al. J Bacteriol. 1970 Mar.

Abstract

Cell-free extracts of Neurospora crassa mycelium catalyze the methylation of l-histidine to form hercynine (histidine betaine). The partially methylated compounds, alpha-N-methyl-l-histidine and alpha-N,N-dimethyl-l-histidine, are also methylated by the same enzyme preparation to form hercynine. All three methylation reactions are stimulated by the addition of S-adenosylmethionine.

PubMed Disclaimer

References

    1. Biochim Biophys Acta. 1967 Sep 12;146(1):111-9 - PubMed
    1. J Bacteriol. 1968 Feb;95(2):340-4 - PubMed
    1. J Med Chem. 1968 Mar;11(2):258-60 - PubMed
    1. J Biol Chem. 1962 May;237:1615-8 - PubMed
    1. J Biol Chem. 1957 Feb;224(2):871-7 - PubMed

LinkOut - more resources