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Comparative Study
. 1979 Dec 15;24(6):786-8.
doi: 10.1002/ijc.2910240615.

Lung carcinoma induction in BD rats after a single intratracheal instillation of an arsenic-containing pesticide mixture formerly used in vineyards

S Ivankovic, G Eisenbrand, R Preussmann
Comparative Study

Lung carcinoma induction in BD rats after a single intratracheal instillation of an arsenic-containing pesticide mixture formerly used in vineyards

S Ivankovic et al. Int J Cancer. .

Abstract

A single intratracheal 0.1-ml instillation of a calcium-arsenate containing vineyard pesticide induced multi-focal bronchogenic adenocarcinomas and bronchiolar-alveolar-cell carcinomas in nine out of 15 treated BD rats. This seems to be the first experimental confirmation of carcinogenicity of arsenic-containing pesticides used formerly in vineyards.

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