Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1970 May;117(4):641-60.
doi: 10.1042/bj1170641.

The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains

E M Press, N M Hogg

The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains

E M Press et al. Biochem J. 1970 May.

Abstract

The amino acid sequences of the Fd fragments of two human pathological immunoglobulins of the immunoglobulin G1 class are reported. Comparison of the two sequences shows that the heavy-chain variable regions are similar in length to those of the light chains. The existence of heavy chain variable region subgroups is also deduced, from a comparison of these two sequences with those of another gamma 1 chain, Eu, a mu chain, Ou, and the partial sequence of a fourth gamma 1 chain, Ste. Carbohydrate has been found to be linked to an aspartic acid residue in the variable region of one of the gamma 1 chains, Cor.

PubMed Disclaimer

References

    1. J Exp Med. 1969 Sep 1;130(3):619-42 - PubMed
    1. Nature. 1967 Dec 2;216(5118):939-41 - PubMed
    1. Nature. 1969 Sep 20;223(5212):1247-8 - PubMed
    1. Hoppe Seylers Z Physiol Chem. 1968 Jul;349(7):945-51 - PubMed
    1. Biochemistry. 1967 Dec;6(12):3957-70 - PubMed