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. 1970 May;117(5):899-905.
doi: 10.1042/bj1170899.

Binding and translation of turnip-yellow-mosaic-virus ribonucleic acid by skeletal-muscle ribosomes from normal and diabetic rats

F S Rolleston, I G Wool, T E Martin

Binding and translation of turnip-yellow-mosaic-virus ribonucleic acid by skeletal-muscle ribosomes from normal and diabetic rats

F S Rolleston et al. Biochem J. 1970 May.

Abstract

Ribosomes from skeletal muscle of diabetic rats were less active than normal ribosomes in protein synthesis directed by turnip-yellow-mosaic-virus RNA. The proportion of ribosomes from muscle of diabetic rats capable of binding turnip-yellow-mosaic-virus RNA was greater than normal, but there was no difference in the equilibrium constants for the binding reaction. The turnip-yellow-mosaic-virus RNA was bound preferentially to the small (40S) ribosomal subunit, whereas the decrease due to diabetes in its translation was associated with the large (60S) subunit. Thus the diminished capacity of ribosomes from muscle of diabetic rats to translate turnip-yellow-mosaic-virus RNA was not the result of decreased binding of the template.

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References

    1. J Mol Biol. 1965 Sep;13(2):511-20 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 May;55(5):1269-76 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 Sep;56(3):991-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 Jun;57(6):1885-92 - PubMed
    1. J Mol Biol. 1967 Sep 14;28(2):211-23 - PubMed