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. 1970 Aug 8;3(5718):324-5.
doi: 10.1136/bmj.3.5718.324.

Simple method for determining isoniazid acetylator phenotype

D W Russell

Simple method for determining isoniazid acetylator phenotype

D W Russell. Br Med J. .

Abstract

Methods have been developed for estimating acetylisoniazid and isoniazid in urine without a spectrophotometer. In experiments with volunteers the ratio of acetylisoniazid to isoniazid in urine samples collected the morning after three spaced oral doses each of 100 mg. was bimodally distributed.

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