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. 1970 Aug 14;169(3946):688-9.
doi: 10.1126/science.169.3946.688.

Lesch-Nyhan syndrome: preventive control by prenatal diagnosis

J A Boyle, K O Raivio, K H Astrin, J D Schulman, M L Graf, J E Seegmiller, C B Jacobsen

Lesch-Nyhan syndrome: preventive control by prenatal diagnosis

J A Boyle et al. Science. .

Abstract

The Lesch-Nyhan syndrome was detected in a fetus at a time sufficiently early to allow termination of the pregnancy. The feasibility of a preventive program for control of a severe sex-linked neurological disease through prenatal diagnosis is thus demonstrated.

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