doi: 10.1126/science.169.3940.74.
Absence of cystathionase in human fetal liver: is cystine essential?
- PMID: 5465366
- DOI: 10.1126/science.169.3940.74
Item in Clipboard
Absence of cystathionase in human fetal liver: is cystine essential?
Science.
.
Abstract
Cystathionase activity is not measurable in the livers of 24 human fetuses and 3 premature infants, and the concentration of cystathionine in the liver is higher than that of the brain. The placenta does not subserve the trans-sulfuration function. Cystine (or cysteine) thus may be an essential amino acid in the immature human.
Similar articles
-
Development of mammalian sulfur metabolism: absence of cystathionase in human fetal tissues.Pediatr Res. 1972 Jun;6(6):538-47. doi: 10.1203/00006450-197206000-00002. Pediatr Res. 1972. PMID: 4625813 No abstract available.
-
Biochemical basis for nutritional management of preterm infants.Pediatrics. 1974 Feb;53(2):147-56. Pediatrics. 1974. PMID: 4149571 Review. No abstract available.
-
Amino acid levels and enzyme activity in tissues of rats force-fed diets differing methionine content.J Nutr. 1969 Oct;99(2):145-51. doi: 10.1093/jn/99.2.145. J Nutr. 1969. PMID: 4390581 No abstract available.
-
Effect of protein intake on tissue amino acid levels and the enzymes of serine biosynthesis in the rat.J Nutr. 1968 Oct;96(2):220-6. doi: 10.1093/jn/96.2.220. J Nutr. 1968. PMID: 4300673 No abstract available.
-
Tissue-specific changes in levels of enzymes of methionine metabolism.Nutr Rev. 1968 Jul;26(7):212-4. doi: 10.1111/j.1753-4887.1968.tb00922.x. Nutr Rev. 1968. PMID: 4875020 Review. No abstract available.
Cited by
-
Comparison of an oral and an intravenous feeding regimen in the newborn.Arch Dis Child. 1974 Mar;49(3):200-4. doi: 10.1136/adc.49.3.200. Arch Dis Child. 1974. PMID: 4207707 Free PMC article.
-
Postnatal hyperoxia exposure differentially affects hepatocytes and liver haemopoietic cells in newborn rats.PLoS One. 2014 Aug 12;9(8):e105005. doi: 10.1371/journal.pone.0105005. eCollection 2014. PLoS One. 2014. PMID: 25115881 Free PMC article.
-
Intravenous feeding in infants.Arch Dis Child. 1971 Dec;46(250):855-63. doi: 10.1136/adc.46.250.855. Arch Dis Child. 1971. PMID: 5001947 Free PMC article. No abstract available.
-
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.J Biol Chem. 2010 Aug 20;285(34):26358-68. doi: 10.1074/jbc.M110.147439. Epub 2010 Jun 21. J Biol Chem. 2010. PMID: 20566639 Free PMC article.
-
Reversible infantile mitochondrial diseases.J Inherit Metab Dis. 2015 May;38(3):427-35. doi: 10.1007/s10545-014-9784-6. Epub 2014 Nov 19. J Inherit Metab Dis. 2015. PMID: 25407320 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
