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. 1970 Jul 3;169(3940):74-6.
doi: 10.1126/science.169.3940.74.

Absence of cystathionase in human fetal liver: is cystine essential?

J A Sturman, G Gaull, N C Raiha

Absence of cystathionase in human fetal liver: is cystine essential?

J A Sturman et al. Science. .

Abstract

Cystathionase activity is not measurable in the livers of 24 human fetuses and 3 premature infants, and the concentration of cystathionine in the liver is higher than that of the brain. The placenta does not subserve the trans-sulfuration function. Cystine (or cysteine) thus may be an essential amino acid in the immature human.

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