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. 1970 Aug;45(242):496-501.
doi: 10.1136/adc.45.242.496.

Albumin excretion as a measure of glomerular dysfunction in children

T M Barratt, P N McLaine, J F Soothill

Albumin excretion as a measure of glomerular dysfunction in children

T M Barratt et al. Arch Dis Child. 1970 Aug.

Abstract

The urine albumin/creatinine concentration ratio (UA/UC) and the albumin excretion rate per unit weight (UAV/Wt) have been compared with the theoretically ideal parameter for measuring glomerular damage, clearance of albumin/clearance of creatinine (CA/CC), using a simple sensitive immunochemical technique for albumin. It is shown that UA/UC on random urine specimens can be as satisfactorily used to predict CA/CC as UAV/Wt. Normal data over a wide range of body size of this simple parameter are presented; higher values in the newborn reflect increased permeability of the neonatal glomerulus.

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