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. 1970 Sep;46(3):471-4.
doi: 10.1104/pp.46.3.471.

Effects of gramicidin on corn mitochondria

R J Miller, W S Dumford, D E Koeppe

Effects of gramicidin on corn mitochondria

R J Miller et al. Plant Physiol. 1970 Sep.

Abstract

The effects of gramicidin D, S, and J on corn mitochondria respiration and swelling were studied. Only gramicidin D was found to have any pronounced effect on mitochondrial swelling. In buffered KCl gramicidin D produced a rapid, respiration-independent swelling which was not reversed with respiratory inhibitors or substrate exhaustion. The respiration rate of exogenous reduced nicotinamide adenine dinucleotide was stimulated by all three gramicidins, but the effects on malate-pyruvate and succinate respiration depended on the type of gramicidin and the reaction media. The respiration effects of gramicidin D may be due to action at specific sites for each substrate.

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References

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    1. Arch Biochem Biophys. 1968 Mar 20;124(1):91-109 - PubMed
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