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. 1970 Oct;46(540):599-605.
doi: 10.1136/pgmj.46.540.599.

Observations on the treatment of rheumatoid disease with penicillamine

Observations on the treatment of rheumatoid disease with penicillamine

J R Golding et al. Postgrad Med J. 1970 Oct.

Abstract

Forty-five patients with severe rheumatoid arthritis were given D-penicillamine hydrochloride according to a fixed regimen for up to 2 years. The effects of treatment were observed both clinically and by the use of laboratory parameters.

The results show that about 75% of patients exhibited objective improvement. Those with rheumatoid arthritis were found to do particularly well. The incidence, type and severity of side-effects are discussed.

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