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. 1970 Nov;104(2):707-11.
doi: 10.1128/jb.104.2.707-711.1970.

Relationship between solute permeability and osmotic remediability in a galactose-negative strain of Saccharomyces cerevisiae

J Bassel, H C Douglas

Relationship between solute permeability and osmotic remediability in a galactose-negative strain of Saccharomyces cerevisiae

J Bassel et al. J Bacteriol. 1970 Nov.

Abstract

An osmotic remedial allele, gal 7-1, in the galactose pathway of Saccharomyces cerevisiae responds to either penetrating (ethylene glycol and diethylene glycol) or nonpenetrating (KCl, NaCl, and sorbitol) solutes in the growth medium. Extracts from cells grown under restrictive conditions gave no increase in enzyme activity (gal-1-phosphate, uridylyl transferase) when exposed to the penetrating solutes; thus protein synthesis or possibly polymer assembly is proposed as the critical step remedied by the addition of the solutes.

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