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. 1976 Feb;73(2):529-33.
doi: 10.1073/pnas.73.2.529.

Biochemistry of the filaments of brain

S H Yen, D Dahl, M Schachner, M L Shelanski

Biochemistry of the filaments of brain

S H Yen et al. Proc Natl Acad Sci U S A. 1976 Feb.

Abstract

Intermediate filaments-cytoplasmic filaments with a diameter of 8-9 nm-have been described in a large variety of cell types. In this study, the subunit protein of the neurofilament and the presumptive subunit of the astroglial filament are compared by immunological and biochemical methods and are found to be very similar. Strong crossreactions are also found between these proteins in a variety of mammalian species. These results suggest that the intermediate filaments may, like microtubules and microfilaments, represent a highly conserved and widely distributed fibrous protein system.

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References

    1. Science. 1975 Mar 14;187(4180):948-50 - PubMed
    1. Nat New Biol. 1971 Oct 27;233(43):283-4 - PubMed
    1. J Neurol Sci. 1974 Dec;23(4):551-63 - PubMed
    1. Science. 1968 Jul 12;161(3837):170-1 - PubMed
    1. Biochemistry. 1969 Dec;8(12):4964-75 - PubMed

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